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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Pignet, AL; Schellnegger, M; Hecker, A; Kohlhauser, M; Kotzbeck, P; Kamolz, LP.
Resveratrol-Induced Signal Transduction in Wound Healing.
Int J Mol Sci. 2021; 22(23):
Doi: 10.3390/ijms222312614
[OPEN ACCESS]
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Pignet Anna-Lisa
- Co-authors Med Uni Graz
- Hecker Andrzej Stanislaw
- Kamolz Lars-Peter
- Kohlhauser Michael
- Kotzbeck Petra
- Schellnegger Marlies
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- Abstract:
- Resveratrol is a well-known polyphenol that harbors various health benefits. Besides its well-known anti-oxidative potential, resveratrol exerts anti-inflammatory, pro-angiogenic, and cell-protective effects. It seems to be a promising adjuvant for various medical indications, such as cancer, vascular, and neurodegenerative diseases. Additionally, resveratrol was shown to display beneficial effects on the human skin. The polyphenol is discussed to be a feasible treatment approach to accelerate wound healing and prevent the development of chronic wounds without the drawback of systemic side effects. Despite resveratrol's increasing popularity, its molecular mechanisms of action are still poorly understood. To take full advantage of resveratrol's therapeutic potential, a profound knowledge of its interactions with its targets is needed. Therefore, this review highlights the resveratrol-induced molecular pathways with particular focus on the most relevant variables in wound healing, namely inflammation, oxidative stress, autophagy, collagen proliferation and angiogenesis.
- Find related publications in this database (Keywords)
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