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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Reishofer, G; Studencnik, F; Koschutnig, K; Deutschmann, H; Gunzer, F; Hassler, E; Leber, SL; Wood, G.
THE INFLUENCE OF SPATIAL RESOLUTION AND FIBER DENSITY ON THE FRACTAL DIMENSION OF CEREBRAL FIBER TRACTS
FRACTALS. 2021; 29(07): 2150232
Doi: 10.1142/S0218348X21502327
Web of Science
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- Leading authors Med Uni Graz
- Reishofer Gernot
- Co-authors Med Uni Graz
- Deutschmann Hannes
- Gunzer Felix
- Hassler Eva Maria
- Koschutnig Karl
- Leber Stefan
- Studencnik Fritz
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- Abstract:
- The determination of the generalized fractal dimensions (FDs) from MRI tractograms is affected by image resolution and the number of fiber tracts. In this work, we demonstrate that only certain combinations of image resolution, number of fiber tracts and exponent of the generalized dimensions are able to capture structural changes in human cerebral white matter. MRI tractography was carried out for a different number of fiber tracts and was discretized on different grid sizes. Generalized FDs were evaluated for two groups of healthy subjects with different age distribution. For the box-counting dimension (q = 0) the highest difference between two age groups was found for a matrix size of 2048(3) pixel with a strong dependence on the number of fiber tracts. The correlation dimension found the highest differences for a resolution of 1024(3) pixel, largely independent of the number of fiber tracts. The correlation dimension evaluated for tractograms discretized on a 1024(3) grid is a robust measurement to capture structural changes in human cerebral white matter by means of FD.
- Find related publications in this database (Keywords)
- Flactal Analysis
- Diffusion-Weighted imaging (DWI)
- Tractography
- Fiber Tracking
- Aging