Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mylrea-Foley, B; Wolf, H; Stampalija, T; Lees, C; Arabin, B; Berger, A; Bergman, E; Bhide, A; Bilardo, CM; Breeze, AC; Brodszki, J; Calda, P; Cetin, I; Cesari, E; Derks, J; Ebbing, C; Ferrazzi, E; Ganzevoort, W; Frusca, T; Gordijn, SJ; Gyselaers, W; Hecher, K; Klaritsch, P; Krofta, L; Lindgren, P; Lobmaier, SM; Marlow, N; Maruotti, GM; Mecacci, F; Myklestad, K; Napolitano, R; Prefumo, F; Raio, L; Richter, J; Sande, RK; Thornton, J; Valensise, H; Visser, GHA; Wee, L, , Truffle-2, Group;TRUFFLE, 2, Authors:;TRUFFLE-2, GROUP, AND, COLLABORATING, AUTHORS;C., Brezinka, Department, of, Obstetrics, and, Gynecology, Medical, University, of, Innsbruck, Innsbruck, Austria;D. Casagrandi, University, College, London, Hospitals, NHS, Foundation, Trust, London, UK;A., Cerny, Department, of, Obstetrics, and, Gynaecology, GeneralUniversity, Hospital, and, First, Faculty, of, Medicine, Charles, University, Prague, Czech, Republic;A., Dall’Asta, Department, of, Obstetrics, and, Gynecology, University, of, Parma, Parma, Italy;R., DeVlieger, Department, of, Gynecology, and, Obstetrics, UZ, Leuven, Leuven, and, Department, of, Regeneration, and, Development, KU, Leuven, Leuven, Belgium;J., Duvekot, Department, of, Obstetrics, and, Gynecology, Erasmus, Academic, Centre, Rotterdam, Rotterdam, The, Netherlands;T., M., Eggebo, St, Olav’s, Hospital, Trondheim, Norway;I., Fantasia, Unit, of, Fetal, Medicine, and, Prenatal, Diagnosis, Institute, for, Maternal, and, Child, Health, IRCCS, Burlo, Garofolo, Trieste, Italy;F., Ferrari, Obstetrics, &, Gynecology, Policlinico, University, Hospital, of, Modena, Modena, Italy;N., Fratelli, Department, of, Obstetrics, and, Gynecology, ASST, Spedali, Civili, di, Brescia, and, University, of, Brescia, Brescia, Italy;T., Ghi, Department, of, Obstetrics, and, Gynecology, University, of, Parma, Parma, Italy;O., Graupner, Department, of, Obstetrics, and, Gynecology, Klinikum, Rechts, Der, Isar, Technical, University, of, Munich, Munich, Germany;P., Greimel, Department, of, Obstetrics, and, Gynecology, Medical, University, of, Graz, Graz, Austria;C., Hofstaetter, Department, of, Obstetrics, &, Gynecology, University, Hospital, of, Bern, Bern, Switzerland;D., Lo, Presti, Department, of, Surgery, Division, of, Obstetrics, and, Gynecology, Tor, Vergata, University, Policlinico, Casilino, Hospital, Rome, Italy;M., Georg, Helsinki, University, Central, Hospital, Helsinki, Finland;F., Macsali, Department, of, Obstetrics, and, Gynecology, Haukeland, University, Hospital, Bergen, Norway;K., Marsal, Department, of, Obstetrics, and, Gynecology, Lund, University, Skåne, University, Hospital, Lund, Sweden;P., Martinelli, Department, of, Neurosciences, Reproductive, and, Dentistry, Sciences, University, of, Naples, ‘Federico, II’, Naples, Italy;E., Ostermayer, Department, of, Obstetrics, and, Gynecology, Klinikum, Rechts, Der, Isar, Technical, University, of, Munich, Munich, Germany;A., Papageorghiou, Fetal, Medicine, Unit, St George’s, University, Hospitals, NHS, Foundation, Trust, and, Molecular, &, Clinical, Sciences, Research, Institute, St George’s, University, of, London, London, UK;R., Peasley, Fetal, Medicine, Unit, University, College, London, Hospitals, NHS, Foundation, Trust, London, UK;A., Ramoni, Department, of, Obstetrics, and, Gynecology, Medical, University, of, Innsbruck, Innsbruck, Austria;L., Sarno, Department, of, Neurosciences, Reproductive, and, Dentistry, Sciences, University, of, Naples, ‘Federico, II’, Naples, Italy;L. ....
Longitudinal Doppler Assessments in Late Preterm Fetal Growth Restriction.
Ultraschall Med. 2023; 44(1):56-67
Doi: 10.1055/a-1511-8293
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Klaritsch Philipp
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- Abstract:
- PURPOSE: To assess the longitudinal variation of the ratio of umbilical and cerebral artery pulsatility index (UCR) in late preterm fetal growth restriction (FGR). MATERIALS AND METHODS: A prospective European multicenter observational study included women with a singleton pregnancy, 32+ 0-36+ 6, at risk of FGR (estimated fetal weight [EFW] or abdominal circumference [AC] < 10th percentile, abnormal arterial Doppler or fall in AC from 20-week scan of > 40 percentile points). The primary outcome was a composite of abnormal condition at birth or major neonatal morbidity. UCR was categorized as normal (< 0.9) or abnormal (≥ 0.9). UCR was assessed by gestational age at measurement interval to delivery, and by individual linear regression coefficient in women with two or more measurements. RESULTS: 856 women had 2770 measurements; 696 (81 %) had more than one measurement (median 3 (IQR 2-4). At inclusion, 63 (7 %) a UCR ≥ 0.9. These delivered earlier and had a lower birth weight and higher incidence of adverse outcome (30 % vs. 9 %, relative risk 3.2; 95 %CI 2.1-5.0) than women with a normal UCR at inclusion. Repeated measurements after an abnormal UCR at inclusion were abnormal again in 67 % (95 %CI 55-80), but after a normal UCR the chance of finding an abnormal UCR was 6 % (95 %CI 5-7 %). The risk of composite adverse outcome was similar using the first or subsequent UCR values. CONCLUSION: An abnormal UCR is likely to be abnormal again at a later measurement, while after a normal UCR the chance of an abnormal UCR is 5-7 % when repeated weekly. Repeated measurements do not predict outcome better than the first measurement, most likely due to the most compromised fetuses being delivered after an abnormal UCR.
- Find related publications in this database (using NLM MeSH Indexing)
- Pregnancy - administration & dosage
- Infant, Newborn - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Fetal Growth Retardation - administration & dosage
- Prospective Studies - administration & dosage
- Ultrasonography, Prenatal - administration & dosage
- Infant, Small for Gestational Age - administration & dosage
- Ultrasonography, Doppler - administration & dosage
- Premature Birth - administration & dosage
- Fetal Weight - administration & dosage
- Gestational Age - administration & dosage
- Umbilical Arteries - diagnostic imaging
- Find related publications in this database (Keywords)
- late fetal growth restriction
- Doppler
- middle cerebral artery
- brain sparing
- adverse outcome