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Schlede, E; Aberer, W; Fuchs, T; Gerner, I; Lessmann, H; Maurer, T; Rossbacher, R; Stropp, G; Wagner, E; Kayser, D.
Chemical substances and contact allergy - 244 substances ranked according to allergenic potency
ALLERGOLOGIE. 2005; 269-286.
Doi: 10.5414/ALP28269
Web of Science
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- Co-Autor*innen der Med Uni Graz
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Aberer Werner
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- Abstract:
- Between 1985 and 2001 a panel of 30 experts (dermatologists and chemical scientist from university, industry and federal offices) evaluated the allergenic potential of 244 chemical substances or chemicals identified as ingredients of natural products. The evaluation process was based on published evidence regarding effects on man, experimental studies, and structure-activity considerations. Category "A" comprised significant contact allergens. Chemicals for which reliable reports regarding sensitizing properties or cross-reactivity were available were ranked in group "B", whereas chemicals with doubtful sensitizing properties and insignificant allergens were classified as "C". The tabulated review comprises 98 substances of category "A", 77 of "B" and 69 of grade "C".
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allergic contact dermatitis
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human and animal data
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potency ranking
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sensitization