Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Domej, W; Flögel, E; Tilz, GP; Demel, U.
Sense and nonsense in antibiotic therapy for respiratory tract infections
INTERNIST 2005 46: 795-799.
Doi: 10.1007/s00108-005-1397-6
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Domej Wolfgang
- Co-Autor*innen der Med Uni Graz
- Demel Ulrike
- Tilz Gernot
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- Abstract:
- Whether an antibiotic successfully eradicates pathogens depends on the pathogens involved, on pharmacokinetics and bioavailability in the target tissue, and on the antimicrobial resistance of the pathogen. Other determinants are drug interactions, individual risk factors, age and compliance with respect to correct dosage and duration of therapy. In many cases, antimicrobial therapy is begun on an empirical basis, because the responsible pathogen can be identified in only half of all respiratory infections. The eradication of the pathogen has to be the first aim if treatment is to be curative and the development of resistance prevented. Long-term prevention of antimicrobial resistance will require a more critical prospective evaluation of the prescription of antibiotics. This paper considers rational and irrational measures in the antimicrobial therapy of respiratory infections.
- Find related publications in this database (using NLM MeSH Indexing)
- Anti-Bacterial Agents - administration and dosage
- Bacterial Infections - drug therapy
- Clinical Trials - drug therapy
- Drug Administration Schedule - drug therapy
- Drug Resistance - drug therapy
- English Abstract - drug therapy
- Evidence-Based Medicine - drug therapy
- Humans - drug therapy
- Practice Guidelines - drug therapy
- Respiratory Tract Infections - drug therapy
- Find related publications in this database (Keywords)
- antibiotic therapy
- antimicrobial resistance
- respiratory tract infection
- pulmonary infection
- microbiology