Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kovacs, G; Olschewski, H.
Challenges in the diagnostics of pulmonary hypertension
PNEUMOLOGE. 2015; 12(5): 381-389.
Doi: 10.1007/s10405-015-0880-6
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Kovacs Gabor
- Co-Autor*innen der Med Uni Graz
- Olschewski Horst
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- Abstract:
- Right heart catheterization represents the gold standard examination for the diagnosis of pulmonary hypertension (PH). Although this method has been used for several decades with only minor technical changes, in the last few years some important challenges have been identified. These mainly involve the early diagnosis and the differential diagnosis of PH. In the field of early diagnosis exercise investigations play an increasingly important role. Current studies suggest that the increase of both mean pulmonary arterial pressure and total pulmonary resistance during exercise may provide a new basis for the definition of exercise PH. In the field of differential diagnostics the classification of cardiac and pulmonary diseases as comorbidities or the cause of PH and the identification of the latent forms can represent a major challenge. The importance of novel non-invasive diagnostic methods has increased in recent years and in several questions these add important information to right heart catheterization data. Simple non-invasive methods can help to identify patients with a very likely or a very unlikely PH. The most important non-invasive method for PH remains echo-cardiography. In addition to classical parameters, novel techniques with prognostic relevance have been established. Tissue Doppler echocardiography and 3-dimensional echocardiography can reliably assess right ventricular function and exercise echocardiography can describe exercise hemodynamics and determine the contractile reserve. Modern imaging methods, including computed tomography (CT) and magnetic resonance imaging (MRI), are very promising in the non-invasive assessment of pulmonary hemodynamics and in upcoming years will most probably play an increasing role in the diagnostic algorithm for PH.
- Find related publications in this database (Keywords)
- Heart catheterization
- Echocardiography
- Exercise
- Differential diagnosis
- Non-invasive diagnostic methods