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Rosenbaum, CM; Schmid, M; Ludwig, TA; Kluth, LA; Dahlem, R; Fisch, M; Ahyai, S.
Redo buccal mucosa graft urethroplasty: success rate, oral morbidity and functional outcomes.
BJU Int. 2016; 118(5):797-803
Doi: 10.1111/bju.13528
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
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Ahyai Sascha
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Leitsmann Marianne
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- Abstract:
- OBJECTIVES: To determine the success rate, oral morbidity and functional outcomes of redo buccal mucosa graft urethroplasty (BMGU) for treatment of stricture recurrence after previous BMGU. PATIENTS AND METHODS: We included 50 patients who underwent redo BMGU between February 2009 and September 2014. Patients' charts and non-validated questionnaires were reviewed. The primary endpoint was success rate, defined as stricture-free survival. Stricture recurrence was defined as any postoperative claims of catheterization, dilatation, urethrotomy or repeat urethroplasty, or a maximum urinary flow rate <15 mL/s, and a stricture was consecutively verified in a combined cysto-urethrogram or cystoscopy at annual follow-up visit. The secondary endpoint was oral morbidity. Additional endpoints were erectile function, urinary continence and patients' satisfaction. RESULTS: Redo BMGU was performed for bulbar (71.4%) or penile (28.6%) recurrent strictures. The mean (median; range) follow-up was 25.6 (15.5; 3-70) months. Stricture recurrence occurred in 18.0% of patients within a mean (median; range) of 13.8 (9.0; 3-36) months. Stricture-free survival at 12, 24 and 36 months was 91.2, 86.2 and 80.8%, respectively. The majority of the patients (97.0%) reported no or only mildly changed salivation or problems in opening of the mouth. Severe or very severe oral numbness occurred in 13.5% of patients. Oral problems in daily life were a moderate or severe burden to 13.6 and 2.7% of the patients, respectively, while 75.0% of the patients reported improved quality of life compared with preoperative status. CONCLUSIONS: The success rate and oral morbidity of redo BMGU are almost the same as outcomes of primary BMGU. Oral numbness was the most frequently reported oral disorder.
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Child, Preschool - administration & dosage
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Humans - administration & dosage
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Infant - administration & dosage
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Male - administration & dosage
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Mouth Diseases - epidemiology
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Mouth Mucosa - transplantation
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Postoperative Complications - epidemiology
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Recovery of Function - administration & dosage
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Recurrence - administration & dosage
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Remission Induction - administration & dosage
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Reoperation - administration & dosage
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Urethra - surgery
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Urethral Stricture - surgery
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Urologic Surgical Procedures, Male - methods
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recurrent urethral stricture
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buccal mucosa graft urethroplasty
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oral morbidity