Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Becker, A; Pradel, L; Kluth, L; Schmid, M; Eichelberg, C; Ahyai, S; Trinh, Q; Seiler, D; Dahlem, R; Hansen, J; Rink, M; Zacharias, M; Mehnert, A; Bergelt, C; Fisch, M; Chun, FK.
Laparoscopic versus open partial nephrectomy for clinical T1 renal masses: no impact of surgical approach on perioperative complications and long-term postoperative quality of life.
World J Urol. 2015; 33(3):421-6
Doi: 10.1007/s00345-014-1318-1
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Ahyai Sascha
- Leitsmann Marianne
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- Abstract:
- OBJECTIVES: Beyond oncological safety, consideration of 30-day complications according to Clavien-Dindo, as well as postoperative quality of life (QoL) after nephron-sparing surgery for clinical T1 renal masses, represents important factors for treatment decision counseling. The objective of this study was to compare the effect of laparoscopic versus open partial nephrectomy (LPN vs. OPN) on 30-day complications and long-term postoperative QoL for clinical T1 renal masses. METHODS: Retrospective, longitudinal analysis of 293 patients treated with either LPN versus OPN for T1 renal masses. The investigated endpoints were 30-day Clavien-Dindo complications and health-related QoL (EORTC QLQ-C30). Respectively, logistic and linear regression models analyzed the effect of surgical partial nephrectomy approach on endpoints. RESULTS: Overall complication rates were similar in patients undergoing OPN or LPN (16.1 vs. 14.6 %, p = 0.8). Significantly less major complications (2.4 vs. 10.4 %, p = 0.025) occurred after LPN. Despite a shorter convalescence period for LPN patients (p = 0.035), in uni- and multivariable analyses, surgical approach was not associated with 30-day complications nor long-term differences in QoL (all p > 0.05). CONCLUSIONS: Despite a faster recovery time after LPN, our findings suggest that LPN and OPN are equivalent with regard to 30-day Clavien-Dindo complication rates and long-term QoL.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Carcinoma, Renal Cell - pathology, surgery
- Female - administration & dosage
- Humans - administration & dosage
- Incidence - administration & dosage
- Intraoperative Complications - epidemiology
- Kidney - innervation, surgery
- Kidney Neoplasms - pathology, surgery
- Laparoscopy - methods
- Longitudinal Studies - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Neoplasm Staging - administration & dosage
- Nephrectomy - methods
- Organ Sparing Treatments - administration & dosage
- Postoperative Complications - epidemiology
- Quality of Life - administration & dosage
- Regression Analysis - administration & dosage
- Retrospective Studies - administration & dosage
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- Renal cell carcinoma
- Renal mass
- Quality of life
- EORTC
- Outcomes
- Complication