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Portoles, J; Krisper, P; Choukroun, G; de Francisco, ALM.
Exploring dosing frequency and administration routes in the treatment of anaemia in CKD patients.
NEPHROL DIALYSIS TRANSPLANT. 2005; 20(S8): 13-17. Doi: 10.1093/ndt/gfh1111 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz
Krisper Peter
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Abstract:
Erythropoiesis-stimulating agents have dramatically changed the management of renal anaemia since their introduction almost 20 years ago. However, optimal dosing route and frequency are still a matter of debate. Intravenous application of recombinant human erythropoietin should be limited to haemodialysis patients and must be given three times weekly, as any reduction to this dosing frequency leads to a major increase in dose requirements. Administering recombinant human erythropoietin-beta once weekly via the subcutaneous route is effective. If conversion from the subcutaneous to the intravenous route is required, dose requirements for recombinant human erythropoietin therapy remain a subject of discussion.
Find related publications in this database (using NLM MeSH Indexing)
Anemia - drug therapy
Chronic Disease - drug therapy
Drug Administration Schedule - drug therapy
Erythropoiesis - drug effects
Erythropoietin, Recombinant - administration and dosage
Humans - administration and dosage
Kidney Diseases - complications
Red-Cell Aplasia, Pure - etiology
Renal Dialysis - etiology

Find related publications in this database (Keywords)
chronic kidney disease
doses and routes
erythropoietin
renal anaemia
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