Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Reitsamer, R; Peintinger, F; Forsthuber, E; Sir, A.
The applicability of Magseed® for targeted axillary dissection in breast cancer patients treated with neoadjuvant chemotherapy.
Breast. 2021; 57:113-117
Doi: 10.1016/j.breast.2021.03.008
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Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Peintinger Florentia
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- Abstract:
- BACKGROUND: Targeted axillary dissection (TAD), the combination of sentinel lymph node biopsy (SLNB) and targeted lymph node biopsy (TLNB), can reduce the false negative rates of sentinel node biopsy alone dramatically in breast cancer patients, who received neoadjuvant chemotherapy (NAC). However methods for TAD are still under investigation. METHODS: Magseed®, a non-radioactive magnetic marker was used to mark the biopsied positive TLN after NAC. The SLNB with the standard technetium-based method and the selective TLNB with Magseed® localization were performed in 40 patients. The TLNs were identified with the Sentimag® probe and excised in all patients. Specimen x-ray was performed to confirm the Magseed® within the prior to NAC biopsied and clipped lymph node. RESULTS: The TLN identification rate was 100% (40/40), the SLN identification rate was 82.5% (33/40), the concordance rate between the TLN and the SLN was 65% (26/40). Complications according Magseed® deployment or identification could not be observed. CONCLUSION: Magseed® is a reliable and feasible marker for the identification of TLNs after NAC.
- Find related publications in this database (using NLM MeSH Indexing)
- Antineoplastic Combined Chemotherapy Protocols - therapeutic use
- Axilla - administration & dosage
- Breast Neoplasms - drug therapy, pathology, surgery
- Female - administration & dosage
- Humans - administration & dosage
- Lymph Node Excision - administration & dosage
- Lymph Nodes - pathology
- Lymphatic Metastasis - administration & dosage
- Neoadjuvant Therapy - administration & dosage
- Neoplasm Seeding - administration & dosage
- Radionuclide Imaging - methods
- Radiopharmaceuticals - administration & dosage
- Sentinel Lymph Node - diagnostic imaging, pathology, surgery
- Sentinel Lymph Node Biopsy - methods
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- Targeted axillary dissection
- Targeted lymph node biopsy
- Magnetic marker