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Selected Publication:

Haeusler, MC; Hoellwarth, ME; Holzer, P.
Paralytic ileus in a fetus-neonate after maternal intake of benzodiazepine.
Prenat Diagn. 1995; 15(12):1165-1167 Doi: 10.1002/pd.1970151214 (- Case Report)
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Leading authors Med Uni Graz
Haeusler Martin
Co-authors Med Uni Graz
Höllwarth Michael
Holzer Peter
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Abstract:
Paralytic ileus of the small bowel was diagnosed in a fetus at 32 weeks' gestation after referral because of polyhydramnios. The mother had taken clonazepam, a benzodiazepine, and carbamazepine during the entire pregnancy for epilepsy. All known causes for the ileus were ruled out and at 20 months the boy has developed normally. We conclude that maternal anticonvulsant drug intake was very likely the cause of the paralytic ileus. This side-effect is known in experimental and clinical pharmacology but has not yet been described in human fetuses.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Anticonvulsants - adverse effects
Carbamazepine - adverse effects Carbamazepine - therapeutic use
Clonazepam - adverse effects Clonazepam - therapeutic use
Epilepsy - drug therapy
Female -
Fetal Diseases - chemically induced
Humans -
Infant, Newborn -
Intestinal Pseudo-Obstruction - chemically induced Intestinal Pseudo-Obstruction - radiography Intestinal Pseudo-Obstruction - ultrasonography
Male -
Pregnancy -
Pregnancy Complications - drug therapy

Find related publications in this database (Keywords)
Paralytic Ileus
Prenatal Diagnosis
Benzodiazepines
Epilepsy
Anticonvulsants
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