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Willem, L; Abrams, S; Libin, PJK; Coletti, P; Kuylen, E; Petrof, O; Møgelmose, S; Wambua, J; Herzog, SA; Faes, C; Beutels, P; Hens, N.
The impact of contact tracing and household bubbles on deconfinement strategies for COVID-19.
Nat Commun. 2021; 12(1): 1524
Doi: 10.1038/s41467-021-21747-7
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- Co-authors Med Uni Graz
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Herzog Sereina Annik
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- Abstract:
- The COVID-19 pandemic caused many governments to impose policies restricting social interactions. A controlled and persistent release of lockdown measures covers many potential strategies and is subject to extensive scenario analyses. Here, we use an individual-based model (STRIDE) to simulate interactions between 11 million inhabitants of Belgium at different levels including extended household settings, i.e., "household bubbles". The burden of COVID-19 is impacted by both the intensity and frequency of physical contacts, and therefore, household bubbles have the potential to reduce hospital admissions by 90%. In addition, we find that it is crucial to complete contact tracing 4 days after symptom onset. Assumptions on the susceptibility of children affect the impact of school reopening, though we find that business and leisure-related social mixing patterns have more impact on COVID-19 associated disease burden. An optimal deployment of the mitigation policies under study require timely compliance to physical distancing, testing and self-isolation.
- Find related publications in this database (using NLM MeSH Indexing)
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Adolescent - administration & dosage
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Adult - administration & dosage
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Aged - administration & dosage
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Aged, 80 and over - administration & dosage
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Belgium - epidemiology
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COVID-19 - epidemiology, transmission
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Child - administration & dosage
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Child, Preschool - administration & dosage
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Communicable Disease Control - methods
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Contact Tracing - administration & dosage
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Disease Transmission, Infectious - prevention & control
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Family Characteristics - administration & dosage
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Health Policy - administration & dosage
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Hospitalization - administration & dosage
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Humans - administration & dosage
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Infant - administration & dosage
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Infant, Newborn - administration & dosage
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Middle Aged - administration & dosage
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Models, Theoretical - administration & dosage
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Pandemics - administration & dosage
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Quarantine - administration & dosage
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SARS-CoV-2 - isolation & purification
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Schools - administration & dosage
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Young Adult - administration & dosage