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Rasmussen, MI; Hansen, ML; Pichler, G; Dempsey, E; Pellicer, A; El-Khuffash, A; A, S; Piris-Borregas, S; Alsina, M; Cetinkaya, M; Chalak, L; Özkan, H; Baserga, M; Sirc, J; Fuchs, H; Ergenekon, E; Arruza, L; Mathur, A; Stocker, M; Otero, Vaccarello, O; Szczapa, T; Sarafidis, K; Królak-Olejnik, B; Memisoglu, A; Reigstad, H; Rafińska-Ważny, E; Hatzidaki, E; Peng, Z; Gkentzi, D; Viellevoye, R; De, Buyst, J; Mastretta, E; Wang, P; Hahn, GH; Bender, L; Cornette, L; Tkaczyk, J; Del, Rio, R; Fumagalli, M; Papathoma, E; Wilinska, M; Naulaers, G; Sadowska-Krawczenko, I; Lecart, C; Couce, ML; Fredly, S; Heuchan, AM; Karen, T; Greisen, G.
Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown.
Front Pediatr. 2021; 9: 647880
Doi: 10.3389/fped.2021.647880
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- Co-Autor*innen der Med Uni Graz
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Pichler Gerhard
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- Abstract:
- Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks of gestational age) differed in the neonatal intensive care units (NICUs) of the SafeBoosC-III consortium during the global lockdown when compared to the corresponding time period in 2019. Design: This is a retrospective, observational study. Forty-six out of 79 NICUs (58%) from 17 countries participated. Principal investigators were asked to report the following information: (1) Total number of EP infant admissions to their NICU in the 3 months where the lockdown restrictions were most rigorous during the first phase of the COVID-19 pandemic, (2) Similar EP infant admissions in the corresponding 3 months of 2019, (3) the level of local restrictions during the lockdown period, and (4) the local impact of the COVID-19 lockdown on the everyday life of a pregnant woman. Results: The number of EP infant admissions during the first wave of the COVID-19 pandemic was 428 compared to 457 in the corresponding 3 months in 2019 (-6.6%, 95% CI -18.2 to +7.1%, p = 0.33). There were no statistically significant differences within individual geographic regions and no significant association between the level of lockdown restrictions and difference in the number of EP infant admissions. A post-hoc analysis based on data from the 46 NICUs found a decrease of 10.3%in the total number of NICU admissions (n = 7,499 in 2020 vs. n = 8,362 in 2019). Conclusion: This ad hoc study did not confirm previous reports of a major reduction in the number of extremely pretermbirths during the first phase of the COVID-19 pandemic. Clinical Trial Registration: ClinicalTrial.gov, identifier: NCT04527601 (registered August 26, 2020), https://clinicaltrials.gov/ct2/show/NCT04527601.
- Find related publications in this database (Keywords)
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extremely preterm
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COVID-19
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randomized clinical trial
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pandemic
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observational study
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neonatal intensive care unit admission