Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Leitner, I; Andrianakis, A; Gellner, V; Kiss, P; Andrianakis, D; Tomazic, PV.
Optic nerve injury in preoperative imaging is associated with visual improvement outcome in endoscopic optic nerve decompression.
Wien Klin Wochenschr. 2022; 134(5-6):185-194
Doi: 10.1007/s00508-021-01915-x
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Andrianakis Alexandros
- Co-Autor*innen der Med Uni Graz
- Gellner Verena
- Kiss Peter
- Tomazic Peter Valentin
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- OBJECTIVE: To evaluate potential clinical parameters having an impact on visual outcome after endoscopic optic nerve decompression in acute optic neuropathy patients. METHODS: A retrospective chart review of patients with acute optic neuropathy, who underwent endoscopic optic nerve decompression between June 2001 and November 2018 at an academic center was performed. Patients were divided into groups according to visual improvement after surgical treatment (yes/no). Following clinical parameters were compared between groups: perioperative steroid use, evidence of optic nerve affection in preoperative neuroimaging, additional optic nerve sheath incision, surgery delay and preoperative C-reactive protein (CRP) levels. Further subgroups analyses were conducted based on etiology (trauma/tumor). RESULTS: Among 32 included cases, 16 patients (50%) reported visual improvement after endoscopic optic nerve decompression. There was no significant difference in visual improvement between etiology subgroups (trauma: n = 9/20 (45%) vs. tumor: n = 7/12 (58.3%), p = 0.465). Tumor subgroup patients with visual improvement had a significantly higher prevalence of optic nerve affection in preoperative neuroimaging than those without visual improvement (p = 0.018, φ = 0.683). Perioperative steroid administration was negatively associated with visual outcome (p = 0.034, φ = 0.375). Nerve sheath incision, surgery delay and preoperative CRP levels did not have a significant impact on visual outcome (p > 0.05). CONCLUSION: Radiological findings can help as an indicator for surgical treatment since an affected optic nerve in preoperative neuroimaging resulted in better visual outcome after surgery. The use of steroids should be considered more carefully since it did not show any beneficial effect.
- Find related publications in this database (using NLM MeSH Indexing)
- Decompression, Surgical - methods
- Humans - administration & dosage
- Optic Nerve - diagnostic imaging, surgery
- Optic Nerve Injuries - complications, diagnosis, surgery
- Retrospective Studies - administration & dosage
- Treatment Outcome - administration & dosage
- Visual Acuity - administration & dosage
- Find related publications in this database (Keywords)
- Acute optic neuropathy
- Optic nerve sheath incision
- Steroid treatment
- Endoscopic sinus surgery