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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Sadoghi, B; Schmid-Zalaudek, K; Zalaudek, I; Fink-Puches, R; Niederkorn, A; Wolf, I; Rohrer, P; Richtig, E.
Prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking.
PLoS One. 2021; 16(7): e0254772
Doi: 10.1371/journal.pone.0254772
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- Leading authors Med Uni Graz
- Richtig Erika
- Sadoghi Birgit
- Co-authors Med Uni Graz
- Fink-Puches Regina
- Rohrer Peter Michael
- Schiefer-Niederkorn Anna
- Schmid-Zalaudek Karin
- Wolf Ingrid
- Zalaudek Iris
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- Abstract:
- BACKGROUND: Melanocytic nevi have a complex evolution influenced by several endogenous and exogenous factors and are known risk factors for malignant melanoma. Interestingly, tobacco use seems to be inversely associated with melanoma risk. However, the association between tobacco use and nevi and lentigines has not yet been evaluated. METHODS: We investigated the prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking in a cohort of 59 smokers and 60 age- and sex-matched nonsmokers, using a questionnaire and performing a total body skin examination by experts. RESULTS: No significant differences were detected between smokers and nonsmokers in the numbers of nevi, atypical nevi, and lentigines in sun-exposed areas (p = 0.966, 0.326, and 0.241, respectively) and in non-sun-exposed areas (p = 0.095, 0.351, and 0.546, respectively). CONCLUSION: Our results revealed no significant differences in the prevalence of nevi, atypical nevi, and lentigines between smokers and nonsmokers in sun-exposed and non-sun-exposed areas.