Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Keller, J; Hammer, HF; Afolabi, PR; Benninga, M; Borrelli, O; Dominguez-Munoz, E; Dumitrascu, D; Goetze, O; Haas, SL; Hauser, B; Pohl, D; Salvatore, S; Sonyi, M; Thapar, N; Verbeke, K; Fox, MR.
European guideline on indications, performance and clinical impact of C-13-breath tests in adult and pediatric patients: An EAGEN, ESNM, and ESPGHAN consensus, supported by EPC
UNITED EUR GASTROENT. 2021; 9(5): 598-625.
Doi: 10.1002/ueg2.12099
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- Co-Autor*innen der Med Uni Graz
- Hammer Heinz
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- Abstract:
- Introduction C-13-breath tests are valuable, noninvasive diagnostic tests that can be widely applied for the assessment of gastroenterological symptoms and diseases. Currently, the potential of these tests is compromised by a lack of standardization regarding performance and interpretation among expert centers. Methods This consensus-based clinical practice guideline defines the clinical indications, performance, and interpretation of C-13-breath tests in adult and pediatric patients. A balance between scientific evidence and clinical experience was achieved by a Delphi consensus that involved 43 experts from 18 European countries. Consensus on individual statements and recommendations was established if >= 80% of reviewers agreed and The guideline gives an overview over general methodology of C-13-breath testing and provides recommendations for the use of C-13-breath tests to diagnose Helicobacter pylori infection, measure gastric emptying time, and monitor pancreatic exocrine and liver function in adult and pediatric patients. Other potential applications of C-13-breath testing are summarized briefly. The recommendations specifically detail when and how individual C-13-breath tests should be performed including examples for well-established test protocols, patient preparation, and reporting of test results. Conclusion This clinical practice guideline should improve pan-European harmonization of diagnostic approaches to symptoms and disorders, which are very common in specialist and primary care gastroenterology practice, both in adult and pediatric patients. In addition, this guideline identifies areas of future clinical research involving the use of C-13-breath tests.
- Find related publications in this database (Keywords)
- breathtest
- diagnosis
- gastroenterology
- gastroparesis
- helicobacter pylori
- liver cirrhosis
- motility
- pancreatic exocrine insufficiency
- pancreatitis