Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Lehrnbecher, T; Simon, A; Laws, HJ; Agyeman, PK; Ammann, RA; Attarbaschi, A; Berger, C; Bochennek, K; Neubert, J; Poyer, F; Scheler, M; Strenger, V; Vieth, S; Zoellner, S; Groll, AH.
[Antibacterial Prophylaxis in Children and Adolescents Undergoing Therapy for Cancer - Statement of the Society of Pediatric Oncology and Hematology (GPOH) and of the German Society for Pediatric Infectious Diseases (DGPI) on Two Current International Guidelines].
Klin Padiatr. 2021; 233(3):101-106
Doi: 10.1055/a-1443-6576
Web of Science
PubMed
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- Strenger Volker
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- Abstract:
- Immunocompromised children and adolescents receiving treatment for cancer have an increased risk for potentially life-threatening infectious complications such as blood stream infections with Gram-positive and Gram-negative pathogens. Therefore, several centers for Pediatric Hematology and Oncology administer antibacterial prophylaxis to these patients to lower morbidity and mortality. Two pediatric specific guidelines on antibacterial prophylaxis were recently published. One of these guidelines was drawn up by an international group of pediatric experts of Europe, North and South America and Australia. The other guideline was prepared by an European group convened at the Eighth European Conference on Infections in Leukaemia (ECIL-8). In this review article, the working groups "Infections" of the Society of Pediatric Oncology and Hematology (GPOH) and "Fever in the neutropenic host" of the German Society for Pediatric Infectious Diseases" (DGPI) summarize the available data from randomized studies, systematic reviews and meta-analyses on antibacterial prophylaxis as well of current data on the emergence of resistance and discuss methodological aspects and the recommendations of the two guidelines.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent - administration & dosage
- Anti-Bacterial Agents - adverse effects
- Child - administration & dosage
- Communicable Diseases - drug therapy
- Europe - administration & dosage
- Hematology - administration & dosage
- Humans - administration & dosage
- Neoplasms - drug therapy
- Find related publications in this database (Keywords)
- Child
- cancer
- bacteremia
- antibacterial prophylaxis
- guideline