Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sabau, A; Daas, L; Behkit, A; Wagenpfeil, S; Langenbucher, A; Ardjomand, N; Flockerzi, E; Seitz, B.
Efficacy, safety, and predictability of transepithelial photorefractive keratectomy: meta-analysis.
J Cataract Refract Surg. 2021; 47(5):634-640
Doi: 10.1097/j.jcrs.0000000000000487
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Ardjomand Navid
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- Abstract:
- PURPOSE: To evaluate the efficacy, safety, and predictability of transepithelial photorefractive keratectomy (TransPRK) for correcting myopia, astigmatism, and hyperopia. SETTING: Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany. DESIGN: Meta-analysis of retrospective or prospective studies. METHODS: Relevant studies were collected from Medline and included when meeting the following predefined criteria: randomized controlled trials, at least 1 of the main outcome measures as efficacy, safety, or predictability, and 1 common TransPRK laser (Schwind Amaris). The parameters estimates and 95% CI were derived from random-effects meta-analysis to account for possible heterogeneity. RESULTS: Because hyperopia studies did not meet the inclusion criteria, the results are centered on myopia and astigmatism. Sixteen studies with a total of 1924 treated eyes were included in the meta-analysis. The mean efficacy, safety, and predictability had a probability of 94% (CI, 0.86-0.97), 0% (CI, 0.00-0.03), and 89% (CI, 0.82-0.93), respectively. The mean correction index, difference vector, and index of success had a value of 1.01 (CI, 1.01-1.02), 0.20 (CI, 0.06-0.34), and 0.12 (CI, 0.07-0.18), respectively. CONCLUSIONS: This summary estimate showed that TransPRK was highly effective, safe, and predictable in correcting myopia and/or astigmatism.
- Find related publications in this database (using NLM MeSH Indexing)
- Astigmatism - surgery
- Germany - administration & dosage
- Humans - administration & dosage
- Lasers, Excimer - therapeutic use
- Photorefractive Keratectomy - administration & dosage
- Prospective Studies - administration & dosage
- Refraction, Ocular - administration & dosage
- Retrospective Studies - administration & dosage
- Treatment Outcome - administration & dosage
- Visual Acuity - administration & dosage