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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Hecker, A; Schellnegger, M; Hofmann, E; Luze, H; Nischwitz, SP; Kamolz, LP; Kotzbeck, P.
The impact of resveratrol on skin wound healing, scarring, and aging.
Int Wound J. 2022; 19(1):9-28
Doi: 10.1111/iwj.13601
[OPEN ACCESS]
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Hecker Andrzej Stanislaw
- Kotzbeck Petra
- Co-authors Med Uni Graz
- Hofmann Elisabeth
- Kamolz Lars-Peter
- Luze Hanna
- Nischwitz Sebastian
- Schellnegger Marlies
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- Abstract:
- Resveratrol is a well-known antioxidant that harbours many health beneficial properties. Multiple studies associated the antioxidant, anti-inflammatory, and cell protective effects of resveratrol. These diverse effects of resveratrol are also potentially involved in cutaneous wound healing, scarring, and (photo-)aging of the skin. Hence, this review highlighted the most relevant studies involving resveratrol in wound healing, scarring, and photo-aging of the skin. A systematic review was performed and the database PubMed was searched for suitable publications. Only original articles in English that investigated the effects of resveratrol in wound healing, scarring, and (photo-)aging of the skin were analysed. The literature search yielded a total of 826 studies, but only 41 studies met the inclusion criteria. The included studies showed promising results that resveratrol might be a feasible treatment approach to support wound healing, counteract excessive scarring, and even prevent photo-aging of the skin. Resveratrol represents an interesting and promising novel therapy regime but to confirm resveratrol-associated effects, more evidence based in vitro and in vivo studies are needed.
- Find related publications in this database (using NLM MeSH Indexing)
- Cicatrix - drug therapy
- Humans - administration & dosage
- Research Design - administration & dosage
- Resveratrol - therapeutic use
- Find related publications in this database (Keywords)
- chronic wound
- resveratrol
- scarring
- skin aging
- wound healing