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SHR Neuro Cancer Cardio Lipid Metab Microb

Worel, N; Shaw, BE; Aljurf, M; Koh, M; Seber, A; Weisdorf, D; Schwartz, J; Galeano, S; Kodera, Y; Eldridge, PW; Hashmi, S; Atsuta, Y; Szer, J; Saber, W; Niederwieser, D; Greinix, HT; Worldwide Network for Blood & Marrow Transplantation.
Changes in Hematopoietic Cell Transplantation Practices in Response to COVID-19: A Survey from the Worldwide Network for Blood & Marrow Transplantation.
TRANSPL CELL THER. 2021; 27(3): 270.e1-270270. Doi: 10.1016/j.jtct.2020.11.019 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Co-authors Med Uni Graz
Greinix Hildegard
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Abstract:
SARS-CoV-2 has spread rapidly worldwide, but the full impact of the COVID-19 pandemic on the field of hematopoietic cell transplantation (HCT) remains unknown. To understand this better, an 18-item online survey was disseminated by the Worldwide Network for Blood & Marrow Transplantation with questions exploring SARS-CoV-2 testing algorithms, mobilization, and cryopreservation strategies and COVID-19 infections in allogeneic related and autologous hematopoietic progenitor cell (HPC) donors. The aim of this survey was to assess the impact of the outbreak on policies relating to HPC mobilization, collection, and processing with respect to changes in daily routine. A total of 91 individual responses from distinct centers in 6 continents were available for analysis. In these centers, the majority (72%) of allogeneic related and autologous donors are routinely tested for SARS-CoV-2 before HPC collection, and 80% of centers implement cryopreservation of allogeneic HPC grafts before commencing conditioning regimens in patients. Five related and 14 autologous donors who tested positive for COVID-19 did not experience any unexpected adverse events or reactions during growth factor administration (eg, hyperinflammatory syndrome). These data are limited by the small number of survey respondents but nonetheless suggest that centers are following the recommendations of appropriate scientific organizations and provide some preliminary data to suggest areas of further study. Copyright © 2020 The American Society for Transplantation and Cellular Therapy. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Algorithms -
Allografts -
Bone Marrow Transplantation - statistics & numerical data
Bone Marrow Transplantation - trends
COVID-19 - diagnosis
COVID-19 - epidemiology
COVID-19 - prevention & control
COVID-19 Testing - methods
COVID-19 Testing - statistics & numerical data
Cryopreservation - methods
Donor Selection - standards
Global Health -
Health Care Surveys -
Hematopoietic Stem Cell Mobilization - statistics & numerical data
Hematopoietic Stem Cell Transplantation - statistics & numerical data
Hematopoietic Stem Cell Transplantation - trends
Pandemics -
Practice Patterns, Physicians' - statistics & numerical data
Procedures and Techniques Utilization - statistics & numerical data
SARS-CoV-2 -
Tissue Preservation - methods
Transplantation, Autologous -
Unrelated Donors - statistics & numerical data

Find related publications in this database (Keywords)
COVID-19
G-CSF
Cryopreservation
Mobilization
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