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Jenks, JD; Nam, HH; Hoenigl, M.
Invasive aspergillosis in critically ill patients: Review of definitions and diagnostic approaches.
Mycoses. 2021; 64(9):1002-1014 Doi: 10.1111/myc.13274 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Co-Autor*innen der Med Uni Graz
Hönigl Martin
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Abstract:
Invasive aspergillosis (IA) is an increasingly recognised phenomenon in critically ill patients in the intensive care unit, including in patients with severe influenza and severe coronavirus disease 2019 (COVID-19) infection. To date, there are no consensus criteria on how to define IA in the ICU population, although several criteria are used, including the AspICU criteria and new consensus criteria to categorise COVID-19-associated pulmonary aspergillosis (CAPA). In this review, we describe the epidemiology of IA in critically ill patients, most common definitions used to define IA in this population, and most common clinical specimens obtained for establishing a mycological diagnosis of IA in the critically ill. We also review the most common diagnostic tests used to diagnose IA in this population, and lastly discuss the most common clinical presentation and imaging findings of IA in the critically ill and discuss areas of further needed investigation.
Find related publications in this database (using NLM MeSH Indexing)
Adult - administration & dosage
Aged - administration & dosage
Aged, 80 and over - administration & dosage
Aspergillus - genetics, isolation & purification
COVID-19 - complications, microbiology
Critical Illness - classification
Diagnostic Techniques and Procedures - standards
Female - administration & dosage
Humans - administration & dosage
Intensive Care Units - standards
Invasive Pulmonary Aspergillosis - classification, diagnosis, physiopathology
Male - administration & dosage
Mannans - blood
Middle Aged - administration & dosage
Polymerase Chain Reaction - administration & dosage
Practice Guidelines as Topic - administration & dosage
SARS-CoV-2 - administration & dosage

Find related publications in this database (Keywords)
Aspergillus galactomannan lateral flow assay
Aspergillus‐
specific lateral flow device
AspICU criteria
COVID‐
associated invasive pulmonary aspergillosis
critically ill patients
EORTC
Galactomannan
influenza‐
associated invasive aspergillosis
intensive care unit
Invasive aspergillosis
MSG criteria
polymerase chain reaction
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