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Seiler, A; Jenewein, J; Martin-Soelch, C; Goetzmann, L; Inci, I; Weder, W; Schuurmans, MM; Benden, C; Brucher, A; Klaghofer, R.
Post-transplant outcome-clusters of psychological distress and health-related quality of life in lung transplant recipients.
Swiss Med Wkly. 2015; 145(6):w14236-w14236
Doi: 10.4414/smw.2015.14236
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PubMed
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- Co-authors Med Uni Graz
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Jenewein Josef
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To (1) assess distinct clusters of psychological distress and health-related quality of life during the first 6 months following lung transplantation; (2) identify patients with poor psychosocial outcomes; and (3) determine potential predictors regarding psychological distress and health-related quality (HRQoL) of life at 6 months post-transplant.
A total of 40 patients were examined for psychological distress (Symptom Checklist short version-9) and quality of life (EuroQOL five-dimension health-related quality of life questionnaire) during their first 6 months post-transplant. Hierarchical cluster analyses were performed to identify specific types of post-transplant outcomes in terms of psychological distress and HRQoL over the first six post-transplant months. Correlational analyses examined medical and psychosocial predictors of the outcome at 6 months post-transplant.
Three distinctive clusters were identified, summarizing either groups of patients with (1) optimal (35%), (2) good (42%), and (3) poor outcome-clusters (23%). The latter tended to be older, to suffer from more severe disease, to have more co-morbidities, to have had a prolonged intensive care unit and/or hospital stay, to have more hospital admissions and were more frequently treated with antidepressants post-transplant. Disease severity, length of stay, quality of life two weeks post-transplant, hospital admissions and use of antidepressants were strong predictors of psychological distress and impaired health-related quality of life at six months of follow-up.
Almost a quarter of the investigated patients suffered from elevated distress and substantially impaired HRQoL, with no improvements over time. Results underscore the psychosocial needs of patients with poor post-transplant outcomes.
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Adult -
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Aged -
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Comorbidity -
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Female -
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Humans -
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Longitudinal Studies -
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Lung Transplantation -
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Male -
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Middle Aged -
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Postoperative Complications -
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Prospective Studies -
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Psychiatric Status Rating Scales -
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Quality of Life - psychology
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Stress, Psychological - diagnosis
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Stress, Psychological -
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Transplant Recipients - psychology
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Young Adult -
- Find related publications in this database (Keywords)
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lung transplantation
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psychological distress
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health-related quality of life