Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Antonijevic, D; Jeschke, A; Colovic, B; Milovanovic, P; Jevremovic, D; Kisic, D; vom Scheidt, A; Hahn, M; Amling, M; Jokanovic, V; Busse, B; Djuric, M.
Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements.
J Endod. 2015; 41(12): 2050-2057.
Doi: 10.1016/j.joen.2015.09.008
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- vom Scheidt Annika
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- Abstract:
- Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials' surface to evaluate their adherence. The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements' surfaces without alteration of the cell structural integrity. YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Calcium Carbonate - chemistry
- Calcium Compounds - chemistry
- Cell Adhesion -
- Dental Cements - chemistry
- Fluorides - chemistry
- Hydrogen-Ion Concentration -
- Hydroxyapatites - chemistry
- Mice -
- Nanoparticles - chemistry
- Osteoblasts - cytology
- Porosity -
- Silicates - chemistry
- Wettability -
- Ytterbium - chemistry
- Find related publications in this database (Keywords)
- Bioactivity
- calcium silicate
- dental cement
- fluoride
- micro computed tomography
- osteoblasts
- reference point indentation