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SHR Neuro Cancer Cardio Lipid Metab Microb
Meyer, M; Schoepf, UJ; Fink, C; Goldenberg, R; Apfaltrer, P; Gruettner, J; Vajcs, D; Schoenberg, SO; Henzler, T.
Diagnostic performance evaluation of a computer-aided simple triage system for coronary CT angiography in patients with intermediate risk for acute coronary syndrome.
Acad Radiol. 2013; 20(8):980-986
Doi: 10.1016/j.acra.2013.02.014
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Apfaltrer Paul
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- Abstract:
- Given the significance of coronary artery disease as the most important socioeconomic health care problem in the Western World, the application of computer-aided simple triage (CAST) systems to this disease would be desirable. In total, 93 patients with acute chest pain and an intermediate risk score for acute coronary syndrome underwent coronary computed tomography angiography (cCTA). Among those, 74 were of adequate image quality for automated analysis by a commercially available CAST system (COR Analyzer, RCADIA, Haifa, Israel). CAST findings were compared to human expert interpretation for the detection of significant stenosis (≥50%) in the left main, left anterior descending, circumflex, right coronary artery, or arterial branches. Further, one inexperienced observer evaluated all studies for significant stenoses alone and after 1 month guided by a CAST system as an initial read. Human expert interpretation identified 37/74 patients with stenosis ≥50%, whereas the CAST detected 45 patients. The CAST system demonstrated a sensitivity of 100%/79% and a specificity of 78%/89% on a per-patient/per-vessel level, respectively. With CAST, the inexperienced readers' per-vessel sensitivity and positive predictive values significantly improved (P = .011, P = .009) from 69% and 41% to 91% and 74%, respectively. The investigated CAST system for automatic stenosis detection can accurately identify patients with coronary artery stenosis ≥50% and may be of use as initial interpretation and triage of cCTA studies as well as a second reader for inexperienced readers, in absence of expert readers. Copyright © 2013 AUR. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Acute Coronary Syndrome - diagnostic imaging
- Acute Coronary Syndrome - epidemiology
- Adult -
- Aged -
- Aged, 80 and over -
- Comorbidity -
- Coronary Angiography - methods
- Coronary Angiography - statistics & numerical data
- Coronary Artery Disease - diagnostic imaging
- Coronary Artery Disease - epidemiology
- Female -
- Germany - epidemiology
- Humans -
- Male -
- Middle Aged -
- Prevalence -
- Radiographic Image Enhancement - methods
- Radiographic Image Interpretation, Computer-Assisted - methods
- Reproducibility of Results -
- Risk Assessment -
- Sensitivity and Specificity -
- Tomography, X-Ray Computed - methods
- Tomography, X-Ray Computed - statistics & numerical data
- Triage - methods
- Triage - statistics & numerical data
- Find related publications in this database (Keywords)
- Coronary CT angiography
- computed-aided detection
- computer-aided simple triage
- chest pain patient triage
- coronary artery stenosis