Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Molenberghs, G; Buyse, M; Abrams, S; Hens, N; Beutels, P; Faes, C; Verbeke, G; Van Damme, P; Goossens, H; Neyens, T; Herzog, S; Theeten, H; Pepermans, K; Abad, AA; Van Keilegom, I; Speybroeck, N; Legrand, C; De Buyser, S; Hulstaert, F.
Infectious diseases epidemiology, quantitative methodology, and clinical research in the midst of the COVID-19 pandemic: Perspective from a European country.
Contemp Clin Trials. 2020; 99: 106189-106189.
Doi: 10.1016/j.cct.2020.106189
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- Co-Autor*innen der Med Uni Graz
- Herzog Sereina Annik
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- Abstract:
- Starting from historic reflections, the current SARS-CoV-2 induced COVID-19 pandemic is examined from various perspectives, in terms of what it implies for the implementation of non-pharmaceutical interventions, the modeling and monitoring of the epidemic, the development of early-warning systems, the study of mortality, prevalence estimation, diagnostic and serological testing, vaccine development, and ultimately clinical trials. Emphasis is placed on how the pandemic had led to unprecedented speed in methodological and clinical development, the pitfalls thereof, but also the opportunities that it engenders for national and international collaboration, and how it has simplified and sped up procedures. We also study the impact of the pandemic on clinical trials in other indications. We note that it has placed biostatistics, epidemiology, virology, infectiology, and vaccinology, and related fields in the spotlight in an unprecedented way, implying great opportunities, but also the need to communicate effectively, often amidst controversy. Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Age Factors -
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- COVID-19 Testing - standards
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- Vaccine development
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