Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Bruckner, M; O'Reilly, M; Lee, TF; Neset, M; Cheung, PY; Schmölzer, GM.
Effects of varying chest compression depths on carotid blood flow and blood pressure in asphyxiated piglets.
Arch Dis Child Fetal Neonatal Ed. 2021; 106(5):553-556
Doi: 10.1136/archdischild-2020-319473
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Krainer Marlies
- Schmölzer Georg
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- Abstract:
- BACKGROUND: Current neonatal resuscitation guidelines recommend chest compressions (CCs) should be delivered to a depth of approximately 1/3 of the anterior-posterior (AP) chest diameter. The aim of the study was to investigate the haemodynamic effects of different CC depths in a neonatal piglet model. METHODS: CCs were performed with an automated CC machine with 33%, 40% and 25% AP chest diameter in all piglets in the same order for a duration of 3 min each. RESULTS: Eight newborn piglets (age 1-3 days, weight 1.7-2.3 kg) were included in the study. Carotid blood flow (CBF) and systolic blood pressure were the highest using a CC depth of 40% AP chest diameter (19.3±7.5 mL/min/kg and 58±32 mm Hg). CONCLUSION: CC depth influences haemodynamic parameters in asphyxiated newborn piglets during cardiopulmonary resuscitation. The highest CBF and systolic blood pressure were achieved using a CC depth of 40% AP chest diameter. TRIAL REGISTRATION NUMBER: PCTE0000148.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals - administration & dosage
- Animals, Newborn - administration & dosage
- Asphyxia Neonatorum - physiopathology, therapy
- Blood Pressure - administration & dosage
- Cardiopulmonary Resuscitation - methods
- Carotid Arteries - physiology
- Disease Models, Animal - administration & dosage
- Humans - administration & dosage
- Infant, Newborn - administration & dosage
- Practice Guidelines as Topic - administration & dosage
- Regional Blood Flow - administration & dosage
- Swine - administration & dosage