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SHR Neuro Cancer Cardio Lipid Metab Microb

Gruber-Moesenbacher, U; Morresi-Hauff, A; Behr, K; Popper, H.
Myopericytoma arising from myopericytosis-a hitherto unrecognized entity within the lung.
Virchows Arch. 2021; 478(5):841-849 Doi: 10.1007/s00428-020-02972-9 [OPEN ACCESS]
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Leading authors Med Uni Graz: Popper Helmuth
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Abstract:: Two cases of myopericytosis combined with pericytoma originating within the lung are reported. These are rare pulmonary tumors. The differential diagnosis for hemangiopericytoma and pericytic tumors with glomus elements is discussed. Both myopericytic lesions mimic other lesions, which are more commonly seen in the lung. Based on the expression of vascular growth factor receptors 2 and 3, an antiangiogenic therapy was suggested for the patient with the myopericytoma. A treatment with an angiogenesis inhibitor resulted in a regression of the tumor, but not the precursor lesion. Probably a more specific therapy using tyrosine kinase inhibitors for VEGFR2/3 might better control these myopericytic proliferations.
Find related publications in this database (Keywords): Myopericytosis; Myopericytoma; Pericytic tumor; Lung