Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Cruz, DC; Sánchez-Murcia, PA; Jørgensen, KA.
Formal asymmetric enone aminohydroxylation: organocatalytic one-pot synthesis of 4,5-disubstituted oxazolidinones.
Chem Commun (Camb). 2012; 48(49):6112-6114
Doi: 10.1039/c2cc32385k
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Sánchez Murcia Pedro Alejandro
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- Abstract:
- A formal asymmetric organocatalytic aminohydroxylation reaction of enones has been achieved via an aziridination-double S(N)2 sequence. As a part of the reaction design, the generated amino alcohol products are isolated as the corresponding oxazolidinones in good yields and excellent stereoselectivities.
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- Catalysis -
- Crystallography, X-Ray -
- Hydroxylation -
- Ketones - chemistry
- Models, Molecular -
- Molecular Structure -
- Oxazolidinones - chemical synthesis
- Oxazolidinones - chemistry
- Stereoisomerism -