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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Saggini, A; Gorkiewicz, G; Cerroni, L.
Cutaneous lymphohistiocytic infiltrates with foamy macrophages: A novel histopathological clue to Stenotrophomonas maltophilia septicemia.
J Cutan Pathol. 2021; 48(1):160-164
Doi: 10.1111/cup.13893
(- Case Report)
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Cerroni Lorenzo
- Gorkiewicz Gregor
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- Abstract:
- The best-known cutaneous manifestations of septicemia in the skin are the so-called "septic vasculitis" and "septic vasculopathy," which represent two sides of the same pathogenetic process. The spectrum of cutaneous presentations of septicemia is, however, more complex, extending beyond septic vasculitis/vasculopathy. We describe the exceptional histopathological findings of skin lesions associated with Stenotrophomonas maltophilia septicemia, featuring a lymphohistiocytic infiltrate characterized by predominance of foamy macrophages containing granular basophilic material negative for PAS, Gram, Fite, and Grocott. Albeit an uncommon occurrence, S. maltophilia septicemia should be included in the broad differential diagnosis of cutaneous lesions occurring in immunocompromised individuals with worsening general conditions. Awareness of these histopathological findings may facilitate the identification of this insidious infectious agent as a source of nosocomial septicemia. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
- Find related publications in this database (Keywords)
- foamy macrophages
- sepsis
- septic vasculitis
- septicemia
- Stenotrophomonas maltophilia