Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Laursen, CB; Davidsen, JR; Van Acker, L; Salzer, HJF; Seidel, D; Cornely, OA; Hoenigl, M; Alastruey-Izquierdo, A; Hennequin, C; Godet, C; Barac, A; Flick, H; Munteanu, O; Van Braeckel, E.
CPAnet Registry-An International Chronic Pulmonary Aspergillosis Registry.
J Fungi (Basel). 2020; 6(3): Doi: 10.3390/jof6030096 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Co-Autor*innen der Med Uni Graz
Flick Holger
Hönigl Martin
Salzer Helmut J. F.
Altmetrics:

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Abstract:
Chronic pulmonary aspergillosis (CPA) is a chronic fungal infection of the lung associated with high morbidity and mortality. The CPA Research network (CPAnet) registry established in 2018 is an international multicenter collaboration aiming to improve CPA knowledge and patient care. This study's aim was to describe the data collection process and content of CPAnet registry with preliminary clinical data. In the CPAnet registry, clinical data are collected through a web-based questionnaire. Data include CPA phenotype, comorbidities, treatment, outcome, and follow-up from several international centers. An exemplary descriptive analysis was performed on 74 patients, who were registered online before April 2020. CPA patients were predominantly (72%) male, 39% had chronic obstructive pulmonary disease, and 68% had a history of smoking. Chronic cavitary pulmonary aspergillosis was the most common CPA subtype (62%). In 32 patients (52%), voriconazole was the preferred first-line therapy. The multicenter multinational CPAnet registry is a valuable approach to gather comprehensive data on a large study population and reflects real-world clinical practice rather than focusing on specific patient populations in more specialized centers. Additional CPA reference centers are being encouraged to join this promising clinical research collaboration.

Find related publications in this database (Keywords)
Aspergillus
chronic pulmonary aspergillosis
diagnosis
treatment
antifungals
registry
international collaboration
CPAnet
© Med Uni Graz Impressum