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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Mayer-Xanthaki, CF; Pregartner, G; Hirnschall, N; Falb, T; Sommer, M; Findl, O; Wedrich, A.
Impact of intraocular lens characteristics on intraocular lens dislocation after cataract surgery.
Br J Ophthalmol. 2021; 105(11):1510-1514
Doi: 10.1136/bjophthalmol-2020-317124
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Mayer-Xanthaki Christoph Fidel
- Co-authors Med Uni Graz
- Falb Thomas
- Pregartner Gudrun
- Sommer Michael
- Wedrich Andreas
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- Abstract:
- BACKGROUND: To assess the influence of intraocular lens (IOL) characteristics on IOL dislocations after cataract surgery. METHODS: Patients who underwent cataract surgery at the Department of Ophthalmology Graz, Austria, between 1996 and 2017 were included and medical records were reviewed. Cox proportional-hazard regression models were used to assess the influence of IOL characteristics on IOL dislocation. RESULTS: From 68 199 eyes out of 46 632 patients (60.2% women, mean age: 73.71 SD±10.82 years), 111 (0.16%) had an in-the-bag (ITB) disloaction and 35 (0.05%) had an out-of-the-bag (OTB) dislocation. The HRs adjusted for predisposing factors significantly associated with a higher risk for an ITB dislocation were 2.35 (95% CI, 1.45 to 3.8) for hydrophilic IOLs, 2.01 for quadripode IOLs (95% CI, 1.04 to 3.86) and 1.61 (95% CI, 1.04 to 2.48) for haptic angulation. A lower risk was observed for three-piece IOLs (HR=0.58, 95% CI, 0.34 to 0.98) and larger overall IOL diameter (HR=0.79, 95% CI, 0.66 to 0.95). For an OTB dislocation, the HR associated with a higher risk was 18.81 (95% CI, 5.84 to 60.58) for silicone IOLs and 2.12 (95% CI, 0.62 to 7.29) for hydrophilic IOLs. Larger overall IOL diameter (HR 0.40, 95% CI; 0.25 to 0.63) showed a lower risk. CONCLUSION: Hydrophilic IOLs, quadripode IOLs and haptic angulation were associated with a higher risk for an ITB dislocation, whereas three-piece IOLs and a larger overall diameter were associated with a lower risk. Risk factors for OTB dislocation were silicone IOLs, hydrophilic IOLs and a smaller overall IOL diameter.
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