Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Aziz, F; Reichardt, B; Sourij, C; Dimai, HP; Reichart, D; Köhler, G; Brodmann, M; Sourij, H.
Epidemiology of major lower extremity amputations in individuals with diabetes in Austria, 2014-2017: A retrospective analysis of health insurance database.
Diabetes Res Clin Pract. 2020; 170:108477
Doi: 10.1016/j.diabres.2020.108477
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- Führende Autor*innen der Med Uni Graz
- Aziz Faisal
- Sourij Harald
- Co-Autor*innen der Med Uni Graz
- Brodmann Marianne
- Dimai Hans Peter
- Köhler Gerd
- Reichart Daniela
- Sourij Caren
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- Abstract:
- AIMS: To describe the incidence, mortality, and trend of major lower extremity amputations (LEA) and to assess risk factors of all-cause mortality after major LEA in individuals with diabetes. METHODS: Procedure codes of major LEA were extracted from the Austrian Health Insurance database (N = 507,180) during 2014-2017 to estimate crude and age-standardized rates per 100,000 population. Short- (30-day, 90-day) and long-term (1-year, 5-year) all-cause mortality after major LEA was estimated from the date of amputation till the date of death. RESULTS: The age-standardized rate of major LEA was 6.44 with an insignificant annual change of 3% (p = 0.825) from 2014 to 2017. Cumulative 30-day mortality was 13.5%, 90-day 22.0%, 1-year 34.4%, and 5-year 66.7%. Age, male sex, above-knee amputation, Charlson index, and heart failure were significantly associated with both short- and long-term mortality. Cancer, dementia, heart failure, peripheral vascular disease, and renal disease were associated with long-term mortality. CONCLUSIONS: The rate of major LEA in individuals with diabetes remained stable during 2014-2017 in Austria. Short- and long-term mortality rates were considerably high after major LEA. Old age, male sex, above-knee amputations, and Charlson Index were significant predictors of both short- and long-term mortality and comorbidities were significant predictors of long-term mortality only.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Aged, 80 and over - administration & dosage
- Amputation - statistics & numerical data, trends
- Austria - epidemiology
- Comorbidity - administration & dosage
- Dementia - epidemiology
- Diabetes Mellitus - epidemiology, mortality
- Female - administration & dosage
- Heart Failure - epidemiology
- Humans - administration & dosage
- Incidence - administration & dosage
- Insurance, Health - administration & dosage
- Kidney Diseases - epidemiology
- Lower Extremity - surgery
- Male - administration & dosage
- Middle Aged - administration & dosage
- Neoplasms - epidemiology
- Peripheral Vascular Diseases - epidemiology
- Retrospective Studies - administration & dosage
- Risk Factors - administration & dosage
- Find related publications in this database (Keywords)
- Amputations
- Incidence
- Mortality
- Diabetes