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Jenks, JD; Cornely, OA; Chen, SC; Thompson, GR; Hoenigl, M.
Breakthrough invasive fungal infections: Who is at risk?
MYCOSES. 2020; 63(10): 1021-1032.
Doi: 10.1111/myc.13148
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
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Hönigl Martin
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- Abstract:
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The epidemiology of invasive fungal infections (IFIs) in immunocompromised individuals has changed over the last few decades, partially due to the increased use of antifungal agents to prevent IFIs. Although this strategy has resulted in an overall reduction in IFIs, a subset of patients develop breakthrough IFIs with substantial morbidity and mortality in this population. Here, we review the most significant risk factors for breakthrough IFIs in haematology patients, solid organ transplant recipients, and patients in the intensive care unit, focusing particularly on host factors, and highlight areas that require future investigation.
© 2020 Wiley-VCH GmbH.
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breakthrough fungal infections
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risk factors