Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Martucci, G; Bonicolini, E; Parekh, D; Thein, OS; Scherkl, M; Amrein, K.
Metabolic and Endocrine Challenges.
Semin Respir Crit Care Med. 2021; 42(1):78-97
Doi: 10.1055/s-0040-1713084
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Amrein Karin
- Co-Autor*innen der Med Uni Graz
- Scherkl Mario
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- Abstract:
- This review aims to provide an overview of metabolic and endocrine challenges in the setting of intensive care medicine. These are a group of heterogeneous clinical conditions with a high degree of overlap, as well as nonspecific signs and symptoms. Several diseases involve multiple organ systems, potentially causing catastrophic dysfunction and death. In the majority of cases, endocrine challenges accompany other organ failures or manifest as a complication of prolonged intensive care unit stay and malnutrition. However, when endocrine disorders present as an isolated syndrome, they are a rare and extreme manifestation. As they are uncommon, these can typically challenge both with diagnosis and management. Acute exacerbations may be elicited by triggers such as infections, trauma, surgery, and hemorrhage. In this complex scenario, early diagnosis and prompt treatment require knowledge of the specific endocrine syndrome. Here, we review diabetic coma, hyponatremia, hypercalcemia, thyroid emergencies, pituitary insufficiency, adrenal crisis, and vitamin D deficiency, highlighting diagnostic tools and tricks, and management pathways through defining common clinical presentations. Thieme. All rights reserved.
- Find related publications in this database (Keywords)
- coma
- critically ill patients
- adrenal crisis
- pituitary insufficiency
- diabetes
- thyroid emergencies