Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hoch, D; Novakovic, B; Cvitic, S; Saffery, R; Desoye, G; Majali-Martinez, A.
Sex matters: XIST and DDX3Y gene expression as a tool to determine fetal sex in human first trimester placenta.
Placenta. 2020; 97:68-70
Doi: 10.1016/j.placenta.2020.06.016
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- Führende Autor*innen der Med Uni Graz
- Hoch Denise
- Tokic Silvija
- Co-Autor*innen der Med Uni Graz
- Desoye Gernot
- Majali Martinez Alejandro
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- Abstract:
- Fetal sex influences placental function as well as maternal and fetal health, being an important factor to consider in pregnancy studies. However, fetal sex determination in the first trimester of pregnancy still faces some technical limitations. Here we describe an RT-qPCR technique to determine fetal sex based on X-inactive specific transcript (XIST) and DEAD-Box helicase 3 Y-linked (DDX3Y) gene expression. This method is straightforward, reliable, fast and applicable on both, placental tissue and primary cells.
- Find related publications in this database (using NLM MeSH Indexing)
- DEAD-box RNA Helicases - genetics
- Female - administration & dosage
- Gene Expression - administration & dosage
- Humans - administration & dosage
- Minor Histocompatibility Antigens - genetics
- Placenta - metabolism
- Pregnancy - administration & dosage
- Pregnancy Trimester, First - genetics, metabolism
- RNA, Long Noncoding - genetics
- Sex Determination Analysis - methods
- Trophoblasts - metabolism
- Find related publications in this database (Keywords)
- Fetal sex
- Placenta
- Trophoblasts
- Early pregnancy
- RT-qPCR