Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Ramos, JG; Fyrdahl, A; Wieslander, B; Thalén, S; Reiter, G; Reiter, U; Jin, N; Maret, E; Eriksson, M; Caidahl, K; Sörensson, P; Sigfridsson, A; Ugander, M.
Comprehensive Cardiovascular Magnetic Resonance Diastolic Dysfunction Grading Shows Very Good Agreement Compared With Echocardiography.
JACC Cardiovasc Imaging. 2020; 13(12):2530-2542
Doi: 10.1016/j.jcmg.2020.06.027
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Reiter Gert
- Reiter Ursula
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- Abstract:
- OBJECTIVES: The aims of this study were to develop a comprehensive cardiovascular magnetic resonance (CMR) approach to diastolic dysfunction (DD) grading and to evaluate the accuracy of CMR in the diagnosis of DD compared with echocardiography. BACKGROUND: Left ventricular DD is routinely assessed using echocardiography. METHODS: Consecutive clinically referred patients (n = 46; median age 59 years; interquartile range: 46 to 68 years; 33% women) underwent both conventional echocardiography and CMR. CMR diastolic transmitral velocities (E and A) and myocardial tissue velocity (e') were measured during breath-hold using a validated high-temporal resolution radial sector-wise golden-angle velocity-encoded sequence. CMR pulmonary artery pressure was estimated from 4-dimensional flow analysis of blood flow vortex duration in the pulmonary artery. CMR left atrial volume was measured using the biplane long-axis area-length method. Both CMR and echocardiographic data were used to perform blinded grading of DD according to the 2016 joint American and European recommendations. RESULTS: Grading of DD by CMR agreed with that by echocardiography in 43 of 46 cases (93%), of which 9% were normal, 2% indeterminate, 63% grade 1 DD, 4% grade 2 DD, and 15% grade 3 DD. There was a very good categorical agreement, with a weighted Cohen kappa coefficient of 0.857 (95% confidence interval: 0.73 to 1.00; p < 0.001). CONCLUSIONS: A comprehensive CMR protocol for grading DD encompassing diastolic blood and myocardial velocities, estimated pulmonary artery pressure, and left atrial volume showed very good agreement with echocardiography.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Diastole - administration & dosage
- Echocardiography - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Magnetic Resonance Spectroscopy - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Predictive Value of Tests - administration & dosage
- Ventricular Dysfunction, Left - administration & dosage
- Find related publications in this database (Keywords)
- diastolic dysfunction
- echocardiography
- magnetic resonance imaging