Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Frohlich-Reiterer, E; Tauschmann, M; Rami-Merhar, B; Mader, JK; Fritsch, M; Steichen-Gersdorf, E; Hofer, SE.
KidsAP: An Artificial Pancreas for Infants with Type 1 Diabetes.
PADIATR PADOL. 2020;
Doi: 10.1007/s00608-020-00787-0
[OPEN ACCESS]
Web of Science
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Fröhlich-Reiterer Elke
- Co-Autor*innen der Med Uni Graz
- Fritsch Maria
- Mader Julia
- Tauschmann Martin
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Type 1 diabetes mellitus (T1D) is one of the most common chronic metabolic diseases in children and adolescents, and infants are becoming increasingly frequently affected. In recent decades great progress has been made in therapy, especially in terms of insulin pumps and systems for continuous glucose monitoring (CGM). Closed-loop systems consist of an insulin pump worn on the body and CGM, and adjust the automated insulin delivery based on the glucose levels determined. "KidsAP" is a multinational project funded by the European Union and coordinated by the University of Cambridge, UK. The Medical Universities of Innsbruck, Vienna, and Graz are amongst other international partners of this project. The aim is the testing of a closed-loop system developed by the University of Cambridge, in very young T1D children aged 1-7 years. The pilot study was successfully carried out in summer 2018. Children wore the closed-loop for a total of 6 weeks in the home environment. Each participant completed two 21-day periods using the closed-loop system with either diluted (U20) or standard (U100) insulin in a randomized cross-over design. Both study arms showed a high time in range, with sensor glucose values between 70 and 180 & x202f;mg/dl.
- Find related publications in this database (Keywords)
- Type 1 diabetes
- Insulin pump
- Continuous glucose monitoring
- Closed-loop system
- Infants