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SHR Neuro Cancer Cardio Lipid Metab Microb

Niederer, SA; Aboelkassem, Y; Cantwell, CD; Corrado, C; Coveney, S; Cherry, EM; Delhaas, T; Fenton, FH; Panfilov, AV; Pathmanathan, P; Plank, G; Riabiz, M; Roney, CH; Dos Santos, RW; Wang, L.
Creation and application of virtual patient cohorts of heart models.
Philos Trans A Math Phys Eng Sci. 2020; 378(2173): 20190558-20190558. Doi: 10.1098/rsta.2019.0558 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Plank Gernot
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Abstract:: Patient-specific cardiac models are now being used to guide therapies. The increased use of patient-specific cardiac simulations in clinical care will give rise to the development of virtual cohorts of cardiac models. These cohorts will allow cardiac simulations to capture and quantify inter-patient variability. However, the development of virtual cohorts of cardiac models will require the transformation of cardiac modelling from small numbers of bespoke models to robust and rapid workflows that can create large numbers of models. In this review, we describe the state of the art in virtual cohorts of cardiac models, the process of creating virtual cohorts of cardiac models, and how to generate the individual cohort member models, followed by a discussion of the potential and future applications of virtual cohorts of cardiac models. This article is part of the theme issue 'Uncertainty quantification in cardiac and cardiovascular modelling and simulation'.
Find related publications in this database (Keywords): simulation; cardiac; virtual patient cohorts; digital twin