Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Eber, B; Schumacher, M; Zweiker, R; Pokan, R; Klein, W.
Nisoldipine in comparison with long-term nitrates
ACTA MED AUST. 1992; 19(5): 137-139.
Web of Science
PubMed
- Co-Autor*innen der Med Uni Graz
- Schumacher Martin
- Zweiker Robert
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- Abstract:
- Nisoldipine represents a new attractive second generation calcium channel blocker of the dihydropyridine-class for the treatment of all types of coronary artery disease. The effect on chronic ischemia is comparable to long-acting nitrates, side-effects have been rarely observed. The advantages will be the high vascular selectivity with only slight negative inotropic effect as well as a long-lasting positive influence on the myocardial metabolism. Up to now, no studies have been reported which compare nisoldipine and long-acting nitrates directly, but this calcium antagonist appears to influence duration and intensity of symptomatic and silent episodes of ischemia similar to the nitrates.
- Find related publications in this database (using NLM MeSH Indexing)
- Angina Pectoris - drug therapy
- Animals - drug therapy
- Coronary Circulation - drug effects
- Coronary Disease - drug therapy
- Coronary Vasospasm - drug therapy
- Humans - drug therapy
- Myocardial Ischemia - drug therapy
- Nisoldipine - therapeutic use
- Nitrates - therapeutic use
- Find related publications in this database (Keywords)
- Nisoldipine
- Long-Acting Nitrates
- Coronary Artery Disease
- Endothelium-Derived Relaxing Factor
- Silent Ischemia