Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Liegl-Atzwanger, B.
The role of pathology in sarcoma.
MEMO-MAG EUR MED ONC. 2020;
Doi: 10.1007/s12254-020-00574-4
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- Leading authors Med Uni Graz
- Liegl-Atzwanger Bernadette
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- Abstract:
- Soft tissue sarcomas are exceedingly rare cancers with more than 100 different histiologic subtypes and tremendous morphologic heterogeneity. Next generation sequencing (NGS) techniques have drastically improved our knowledge about these tumours. The possibility to use these techniques routinely changed the diagnostic standards in soft tissue pathology. Within the last few years pathologists were confronted with a growing number of exceedingly rare, partly molecularly defined, tumour entities. The proposed pathologic diagnosis dictates prognosis and treatment. Therefore, specialized soft tissue pathology units with the possibility to include molecular diagnostics into a histopathological report for diagnostic, predictive and prognostic aspects are needed. A second opinion by a soft tissue pathologist, before final treatment decision, should be mandatory to ensure optimal treatment for all patients by a multidisciplinary team in a specialized centre.
- Find related publications in this database (Keywords)
- Sarcoma
- Next generation sequencing
- Second opinion
- Liposarcoma
- Leiomyosarcoma