Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Apfaltrer, G; Dutschke, A; Baltzer, PAT; Schestak, C; Özsoy, M; Seitz, C; Veser, J; Petter, E; Helbich, TH; Ringl, H; Apfaltrer, P.
Substantial radiation dose reduction with consistent image quality using a novel low-dose stone composition protocol.
World J Urol. 2020; 38(11):2971-2979
Doi: 10.1007/s00345-020-03082-6
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Apfaltrer Georg
- Apfaltrer Paul
- Co-Autor*innen der Med Uni Graz
- Dutschke Anja
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- Abstract:
- PURPOSE: To assess a novel low-dose CT-protocol, combining a 150 kV spectral filtration unenhanced protocol (Sn150 kVp) and a stone-targeted dual-energy CT (DECT) in patients with urolithiasis. METHODS: 232 (151 male, 49 ± 16.4 years) patients with urolithiasis received a low-dose non-contrast enhanced CT (NCCT) for suspected urinary stones either on a third-generation dual-source CT system (DSCT) using Sn150 kVp (n = 116, group 1), or on a second-generation DSCT (n = 116 group 2) using single energy (SE) 120 kVp. For group 1, a subsequent dual-energy CT (DECT) with a short stone-targeted scan range was performed. Objective and subjective image qualities were assessed. Radiation metrics were compared. RESULTS: 534 stones (group 1: n = 242 stones; group 2: n = 292 stones) were found. In group 1, all 215 stones within the stone-targeted DECT-scan range were identified. DE analysis was able to distinguish between UA and non-UA calculi in all collected stones. 11 calculi (5.12%) were labeled as uric acid (UA) while 204 (94.88%) were labeled as non-UA calculi. There was no significant difference in overall Signal-to-noise-ratio between group 1 and group 2 (p = 0.819). On subjective analysis both protocols achieved a median Likert rating of 2 (p = 0.171). Mean effective dose was significantly lower for combined Sn150 kVp and stone-targeted DECT (3.34 ± 1.84 mSv) compared to single energy 120 kVp NCCT (4.45 ± 2.89 mSv) (p < 0.001), equaling a 24.9% dose reduction. CONCLUSION: The evaluated novel low-dose stone composition protocol allows substantial radiation dose reduction with consistent high diagnostic image quality.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Aged - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Radiation Dosage - administration & dosage
- Retrospective Studies - administration & dosage
- Tomography, X-Ray Computed - methods
- Urinary Calculi - diagnostic imaging
- Find related publications in this database (Keywords)
- Urolithiasis
- Multi-detector computed tomography
- Low-dose CT
- Dual-energy CT