Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hoyer, DP; Kaiser, GM; Treckmann, JW; Mathe, Z; Saner, F; Radunz, S; Bankfalvi, A; Gallinat, A; Minor, T; Paul, A.
AST 17600 U/l after liver transplantation, what are you up to? - A case report.
Ann Transplant. 2013; 18:218-222
Doi: 10.12659/AOT.883910
(- Case Report)
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Mathe Zoltan
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- Abstract:
- Miscellaneous clinical classifications of liver function after liver transplantation are rested upon elevation of transaminases which represent damaging of hepatocytes and with it of the liver. We report the case of a 35-year-old man suffering from hepatocellular carcinoma in the setting of alcoholic liver cirrhosis. The patient underwent liver transplantation and developed an extreme peak of transaminases due to prolonged cold ischemia time and additional extended donor criteria. On the first postoperative day the laboratory results showed peak transaminases as follows: AST 17577 U/l and ALT 9884 U/l. Frequent ultrasound revealed no signs of vascular complications. In spite of the dramatically elevated transaminases the liver showed a good primary function and the patient was cardiopulmonary stable. The entire postoperative course was uneventful. We discharged the patient after three weeks in a very good general state of health, with normal laboratory values. Exclusive extreme elevation of transaminases after liver transplantation combined with adequate liver synthesis does not always require re-transplantation, if situation of the patient is stable. Nevertheless re-transplantation should be reconsidered in any case of clinical deterioration of the patient.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Alanine Transaminase - blood
- Aspartate Aminotransferases - blood
- Carcinoma, Hepatocellular - complications
- Carcinoma, Hepatocellular - surgery
- Cold Ischemia - adverse effects
- Humans -
- Liver - blood supply
- Liver - diagnostic imaging
- Liver - physiopathology
- Liver Cirrhosis, Alcoholic - complications
- Liver Cirrhosis, Alcoholic - surgery
- Liver Function Tests -
- Liver Neoplasms - complications
- Liver Neoplasms - surgery
- Liver Transplantation - adverse effects
- Male -
- Tissue Donors -
- Ultrasonography -
- Find related publications in this database (Keywords)
- elevated transaminases
- liver transplantation
- case report
- extended criteria donor
- clinical decision making