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Vernadakis, S; Saner, FH; Rath, PM; Kaiser, GM; Mathe, Z; Treckmann, J; Paul, A.
Successful salvage therapy with daptomycin after linezolid and vancomycin failure in a liver transplant recipient with methicillin-resistant Staphylococcus aureus endocarditis.
Transpl Infect Dis. 2009; 11(4):346-348
Doi: 10.1111/j.1399-3062.2009.00403.x
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
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Mathe Zoltan
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- Abstract:
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Infective endocarditis is a rare complication affecting solid organ transplant recipients. Staphylococcus aureus is a common cause of infective endocarditis accounting for about 30% of cases. We present a case of nosocomial methicillin-resistant S. aureus endocarditis with persistent bacteremia, in a patient following orthotopic liver transplantation. We were unable to eradicate this infection with primary linezolid therapy or with secondary treatment with combined vancomycin and rifampicin, but successfully treated it with daptomycin, in addition to tricuspid and aortic valve replacement.
- Find related publications in this database (using NLM MeSH Indexing)
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Acetamides - therapeutic use
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Anti-Bacterial Agents - therapeutic use
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Anti-Infective Agents - therapeutic use
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Bacteremia - drug therapy
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Bacteremia - microbiology
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Cross Infection - drug therapy
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Cross Infection - microbiology
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Daptomycin - therapeutic use
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Endocarditis, Bacterial - drug therapy
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Endocarditis, Bacterial - microbiology
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Humans -
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Linezolid -
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Liver Transplantation - adverse effects
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Male -
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Methicillin-Resistant Staphylococcus aureus - drug effects
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Middle Aged -
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Oxazolidinones - therapeutic use
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Salvage Therapy -
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Staphylococcal Infections - drug therapy
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Treatment Failure -
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Treatment Outcome -
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Vancomycin - therapeutic use
- Find related publications in this database (Keywords)
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endocarditis
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liver transplantation
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methicillin-resistant Staphylococcus aureus (MRSA)
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daptomycin
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linezolid