Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Schroeder, T; Sotiropoulos, GC; Molmenti, EP; Kuehl, H; Cicinnati, VR; Schmitz, KJ; Kóbori, L; Paul, A; Mathé, Z.
Changes in staging for hepatocellular carcinoma after radiofrequency ablation prior to liver transplantation as found in the explanted liver.
Hepatogastroenterology. 2012; 58(112):2029-2031
Doi: 10.5754/hge10601
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Mathe Zoltan
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- Abstract:
- To analyze the efficacy of radiofrequency ablation (RFA) prior to liver transplantation (LT) in liver explants. We reviewed pathological findings in the explanted livers of 13 patients with histologically proven HCC and liver cirrhosis who underwent RFA as bridging treatment prior to LT. Eight patients had solitary nodules with a median diameter of 4cm, whereas five patients had two tumors each with a median total diameter of 3.3cm prior to RFA. One session of RFA was performed by all patients. Tumor regression was proved in 3/13 patients whereas steady disease was observed in 5/13 patients (38%). Tumor regression was observed only in one of the five patients having two tumors prior to RFA. Pathology proved a multifocal tumor in four patients, including one patient with a radiological presumed solitary tumor. Tumor progression was observed in 5/13 patients (38%). Although the majority of our patients (8/13, 62%) had a solitary tumor at the beginning of treatment, tumor progression was observed in a large proportion (38%) among them. The underestimation of tumor lesions in radiology and partial necrosis of the tumor achieved in most patients limit the role of RFA as bridging treatment prior to LT.
- Find related publications in this database (using NLM MeSH Indexing)
- Catheter Ablation -
- Disease Progression -
- Humans -
- Liver Neoplasms - pathology
- Liver Neoplasms - surgery
- Liver Transplantation -
- Neoplasm Staging -
- Find related publications in this database (Keywords)
- Radiofrequency ablation
- RFA
- Bridging treatments
- Hepatocellular carcinoma
- Liver transplantation
- Tumor staging