Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Burch, AE; D'Souza, B; Gimbel, JR; Rohrer, U; Masuda, T; Sears, S; Scherr, D.
Physical activity is reduced prior to ventricular arrhythmias in patients with a wearable cardioverter defibrillator.
Clin Cardiol. 2020; 43(1):60-65
Doi: 10.1002/clc.23288
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- Co-Autor*innen der Med Uni Graz
- Rohrer Ursula
- Scherr Daniel
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- Abstract:
- The utility of accelerometer-based activity data to identify patients at risk of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) has not previously been investigated. The aim of the current study was to determine whether physical activity is associated with manifesting spontaneous sustained VT/VF requiring emergent defibrillation in patients with an ejection fraction of ≤35%. Patients consecutively prescribed a wearable cardioverter defibrillator (WCD) from April 2015 to May 2018 were included. Shock data and 4 weeks of physical activity data, beginning with the first week of WCD wear, were analyzed. Based on the ROC curve outcome generated from 4057 patients, average daily step count during the first week accurately predicted those patients with sustained VT/VF compared to those without (shocked (n = 81) vs nonshocked (n = 3976) area under the curve, c-index = 0.71, 95% CI = 0.65-0.77, P < .001). An average cutoff of 3637 daily steps during week 1 separated the groups. Patients who averaged fewer than 3637 steps per day during the first week of WCD use were 4.3 times more likely to experience a shock than those who walked more than 3637 steps per day (OR = 4.29, 95% CI = 2.58-7.15, P < .001). Average daily step counts are lower in WCD patients who manifest spontaneous VT/VF. Whether these findings represent a causal or correlational relationship, future studies to encourage a minimum daily step count in high-risk patients may impact the incidence of sustained VT/VF. © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.
- Find related publications in this database (using NLM MeSH Indexing)
- Accelerometry -
- Aged -
- Defibrillators, Implantable -
- Electrocardiography -
- Exercise - physiology
- Female -
- Humans -
- Male -
- Middle Aged -
- Patient Compliance -
- Retrospective Studies -
- Tachycardia, Ventricular - diagnosis
- Tachycardia, Ventricular - physiopathology
- Tachycardia, Ventricular - therapy
- Ventricular Fibrillation - diagnosis
- Ventricular Fibrillation - physiopathology
- Ventricular Fibrillation - therapy
- Wearable Electronic Devices -
- Find related publications in this database (Keywords)
- activity
- ventricular arrhythmia
- wearable cardioverter defibrillator