Gewählte Publikation:
Pilger, E; Lammer, J; Bertuch, H; Stark, G; Decrinis, M; Pfeiffer, KP; Krejs, GJ.
Nd:YAG laser with sapphire tip combined with balloon angioplasty in peripheral arterial occlusions. Long-term results.
Circulation. 1991; 83(1):141-147
Doi: 10.1161/01.CIR.83.1.141
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- Führende Autor*innen der Med Uni Graz
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Pilger Ernst
- Co-Autor*innen der Med Uni Graz
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Krejs Günter Josef
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- Abstract:
- In 167 patients with complete occlusion (greater than 3 cm) of the femoropopliteal artery, percutaneous transluminal laser angioplasty (PTLA) was performed after an unsuccessful attempt at crossing with a guide wire and was immediately followed by balloon dilatation. An Nd-YAG laser and an optical fiber delivery system with a sapphire tip serving as a contact probe were used for PTLA. In 132 of 167 (79%) patients, the occluded segment was successfully reopened. Clinical symptoms improved in 126 of 167 (75%) patients. PTLA was unsuccessful in 35 patients, and in 15 of these, injury of the vessel wall occurred. In one patient, surgical drainage of a large hematoma became necessary. All patients in whom recanalization had been achieved were randomized to receive long-term treatment with either phenprocumarol or acetylsalicylic acid (ASA) plus dipyridamole to prevent rethrombosis. At 36 months of follow-up, the cumulative patency rate (CPR) was 63%. A complete reobstruction in 32 patients (24%) and a partial reobstruction in 15 patients (11%) were found angiographically. The CPR after 36 months was significantly lower (p less than 0.05) in patients younger than 60 years of age (54%) than in patients older than 60 (68%); it was also significantly lower (p less than 0.05) in patients with reduced peripheral runoff (55%) due to obstructed arteries of the lower leg than in patients with unaffected runoff (73%). The CPR was 65% in recanalized segments shorter than 7 cm and was 62% in recanalized segments longer than 7 cm.(ABSTRACT TRUNCATED AT 250 WORDS)
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Aged -
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Angioplasty, Balloon -
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Angioplasty, Laser -
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Arterial Occlusive Diseases - therapy
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Aspirin - therapeutic use
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Dipyridamole - therapeutic use
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Female -
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Femoral Artery -
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Follow-Up Studies -
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Humans -
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Male -
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Phenprocoumon - therapeutic use
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Popliteal Artery -
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Recurrence -
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Time Factors -
- Find related publications in this database (Keywords)
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Vascular Occlusive Disease
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Phenprocumarol
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Acetylsalicylic Acid
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Laser