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SHR Neuro Cancer Cardio Lipid Metab Microb
Sarny, S; Beham-Schmid, C; El-Shabrawi, Y.
Choroidal Infiltration as First Clinical Manifestation of T-cell Large Granular Lymphocyte (T-LGL) Leukemia.
Ocul Immunol Inflamm. 2020; 28(7):1133-1135
Doi: 10.1080/09273948.2019.1645186
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Sarny Stephanie
- Co-authors Med Uni Graz
- Beham-Schmid Christine
- El-Shabrawi Yosuf
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- Abstract:
- Purpose: To report of a 55-year-old woman suffering from choroidal infiltrates as a first clinical manifestation of T-LGL leukemia. Methods: Retrospective case report. Results: A healthy woman presented with photophobia in both eyes since 1 month. She showed a panuveitis with anterior chamber as well as vitreous cells, creamy-white choroidal lesions in both eyes and a cystoid macular edema in the left eye. Lab testing showed only a moderate lymphocytosis, all other tests, including a pars plana vitrectomy and an anterior chamber tap, were negative. Due to the persistent lymphocytosis, she was referred to the oncologist. A biopsy of the bone marrow revealed T-LGL leukemia. A subsequent biopsy of the choroid showed an infiltration of T-LGL and therefore systemic therapy with cyclophosphamide was started. Conclusions: This is a very rare case describing an involvement of the choroid in T-LGL leukemia.
- Find related publications in this database (Keywords)
- Choroidal biopsy
- choroiditis
- cyclophosphamide
- T-LGL leukemia
- uveitis