Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schnuch, A; Geier, J; Uter, W; Frosch, PJ; Lehmacher, W; Aberer, W; Agathos, M; Arnold, R; Fuchs, T; Laubstein, B; Lischka, G; Pietrzyk, PM; Rakoski, J; Richter, G; Ruëff, F.
National rates and regional differences in sensitization to allergens of the standard series. Population-adjusted frequencies of sensitization (PAFS) in 40,000 patients from a multicenter study (IVDK).
Contact Dermatitis. 1997; 37(5):200-209
Doi: 10.1111/j.1600-0536.1997.tb02435.x
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Aberer Werner
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Sensitization rates to contact allergens vary between centers and are influenced by sex and age. Eliminating the latter 2 factors by standardization of data by age and sex, the present analysis addresses possible differences between centers remaining after elimination of these confounders, and analyzes other factors which might influence rates, e.g., the MOAHL index. Overall standardized rates were well within the range reported in previous studies and may be regarded as representing the rates of the "patch test population" in Central Europe (e.g., nickel sulfate 12.9%, fragrance mix 10.5%, balsam of Peru 7.3%, thimerosal 5.6%). For this analysis, data of those departments which contributed more than 2000 patients, or of those with extreme proportions concerning sex, age and occupational cases were selected. Patients from these 10 departments differed considerably with regard to the items of the MOAHL index and with regard to standardized rates. The items of the MOAHL index proved to be suitable for describing different patch test populations and for explaining some differences between centers. Only 'atopic dermatitis' seems to have little influence on (standardized) rates. Face dermatitis is not yet represented in the MOAHL index, but should be included, together with age > 40 years, in an extended index (acronym: MOAHLFA). Regional allergen exposure (with striking differences between East Germany, West Germany and, to a lesser extent, Austria) seems to have a great influence on the sensitization pattern observed in a department. In addition, sociological factors may influence sensitization rates, which is exemplified by high rates of nickel allergy in a socially defined subgroup. Future studies should focus on these factors, as well as on factors concerning patch test practices and quality control.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Age Distribution -
- Aged -
- Allergens - administration and dosage
- Dermatitis, Allergic Contact - diagnosis
- Desensitization, Immunologic - methods
- Evaluation Studies - methods
- Female - methods
- Germany - epidemiology
- Humans - epidemiology
- Male - epidemiology
- Middle Aged - epidemiology
- Patch Tests - standards
- Prevalence - standards
- Sex Distribution - standards
- Find related publications in this database (Keywords)
- Prevalence
- Contact Sensitization
- Age Standardization
- Sex
- Clinical Epidemiology
- Moahl Index
- Geographical Differences
- Sociology
- Occupational Dermatitis
- Multicenter Study