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Mader, JK; Motschnig, M; Theiler-Schwetz, V; Eibel-Reisz, K; Reisinger, AC; Lackner, B; Augustin, T; Eller, P; Mirth, C.
Feasibility of Blood Glucose Management Using Intra-Arterial Glucose Monitoring in Combination with an Automated Insulin Titration Algorithm in Critically Ill Patients.
Diabetes Technol Ther. 2019; 21(10):581-588
Doi: 10.1089/dia.2019.0082
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Eller Philipp
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Mader Julia
- Co-Autor*innen der Med Uni Graz
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Reisinger Alexander Christian
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Theiler-Schwetz Verena
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Wimmer Melanie
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- Abstract:
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Background:
This two-center pilot study combined for the first time an intra-arterial glucose sensor with a decision support system for insulin dosing (SGCplus system) in critically ill patients with hyperglycemia.
Methods:
Twenty-two patients who were equipped with an arterial line and required iv insulin therapy were managed by the SGCplus system during their medical treatment at the intensive care unit.
Results:
Time to target was 111 ± 195 min (80-150 mg/dL) and 135 ± 267 min (100-160 mg/dL) in the lower and higher glucose target group. Mean blood glucose (BG) was 142 ± 32 mg/dL with seven BG values <70 mg/dL. Mean daily insulin dose was 62 ± 38 U and mean daily carbohydrate intake 148 ± 50 g/day (enteral nutrition) and 102 ± 58 g/day (parenteral nutrition). Acceptance of SGCplus suggestions was high (93%).
Conclusions:
The SGCplus system can be safely applied in critically ill patients with hyperglycemia and enables good glycemic control.
- Find related publications in this database (Keywords)
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Hyperglycemia
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Sensors
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Type 1 diabetes
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Type 2 diabetes
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Intensive care unit
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Insulin dosing algorithm
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Intra-arterial glucose sensing
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Critically ill patients