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Mader, JK; Motschnig, M; Theiler-Schwetz, V; Eibel-Reisz, K; Reisinger, AC; Lackner, B; Augustin, T; Eller, P; Mirth, C.
Feasibility of Blood Glucose Management Using Intra-Arterial Glucose Monitoring in Combination with an Automated Insulin Titration Algorithm in Critically Ill Patients.
Diabetes Technol Ther. 2019; 21(10):581-588 Doi: 10.1089/dia.2019.0082
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Führende Autor*innen der Med Uni Graz
Eller Philipp
Mader Julia
Co-Autor*innen der Med Uni Graz
Reisinger Alexander Christian
Theiler-Schwetz Verena
Wimmer Melanie
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Abstract:
Background: This two-center pilot study combined for the first time an intra-arterial glucose sensor with a decision support system for insulin dosing (SGCplus system) in critically ill patients with hyperglycemia. Methods: Twenty-two patients who were equipped with an arterial line and required iv insulin therapy were managed by the SGCplus system during their medical treatment at the intensive care unit. Results: Time to target was 111 ± 195 min (80-150 mg/dL) and 135 ± 267 min (100-160 mg/dL) in the lower and higher glucose target group. Mean blood glucose (BG) was 142 ± 32 mg/dL with seven BG values <70 mg/dL. Mean daily insulin dose was 62 ± 38 U and mean daily carbohydrate intake 148 ± 50 g/day (enteral nutrition) and 102 ± 58 g/day (parenteral nutrition). Acceptance of SGCplus suggestions was high (93%). Conclusions: The SGCplus system can be safely applied in critically ill patients with hyperglycemia and enables good glycemic control.

Find related publications in this database (Keywords)
Hyperglycemia
Sensors
Type 1 diabetes
Type 2 diabetes
Intensive care unit
Insulin dosing algorithm
Intra-arterial glucose sensing
Critically ill patients
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