Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Francic, V; Keppel, M; Schwetz, V; Trummer, C; Pandis, M; Borzan, V; Grübler, MR; Verheyen, ND; Kleber, ME; Delgado, G; Moissl, AP; Dieplinger, B; März, W; Tomaschitz, A; Pilz, S; Obermayer-Pietsch, B.
Are soluble ST2 levels influenced by vitamin D and/or the seasons?
ENDOCR CONNECT. 2019; 8(6): 691-700.
Doi: 10.1530/EC-19-0090
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- Führende Autor*innen der Med Uni Graz
- Francic Vito
- Co-Autor*innen der Med Uni Graz
- Borzan Valentin
- Grübler Martin
- Keppel Martin Helmut
- März Winfried
- Obermayer-Pietsch Barbara
- Pandis Marlene
- Pilz Stefan
- Theiler-Schwetz Verena
- Tomaschitz Andreas
- Trummer Christian
- Verheyen Nicolas Dominik
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- Abstract:
- OBJECTIVE: Cardiovascular disease manifestation and several associated surrogate markers, such as vitamin D, have shown substantial seasonal variation. A promising cardiovascular biomarker, soluble ST2 (sST2), has not been investigated in this regard – we therefore determined if systemic levels of sST2 are affected by seasonality and/or vitamin D in order to investigate their clinical interrelation and usability. DESIGN: sST2 levels were measured in two cohorts involving hypertensive patients at cardiovascular risk, the Styrian Vitamin D Hypertension Trial (study A; RCT design, 8 weeks 2800 IU cholecalciferol daily) and the Ludwigshafen Risk and Cardiovascular Health Study (LURIC; study B; cross-sectional design).
- Find related publications in this database (Keywords)
- soluble ST2
- seasonality
- vitamin D
- biomarker
- cardiovascular disease